Morphine Base is the primary natural opioid alkaloid and one of the most strategic pharmaceutical intermediates manufactured by Parand Darou Co. It serves as a vital raw material and key precursor in the synthesis of various pharmaceutical salts, including Morphine Sulfate, Morphine Hydrochloride, and other semi-synthetic opioid analgesics and receptor agonists.
Pharmacological Significance
Morphine Base constitutes the foundation for producing narcotic analgesics essential for managing severe acute and chronic pain, including post-surgical, traumatic, and oncological pain. By binding specifically to the mu (μ) opioid receptors in the central nervous system, this molecule provides exceptional analgesic effects. The high-purity synthesis of this intermediate ensures the quality, stability, and clinical efficacy of final injectable and oral dosage forms.
Quality Assurance & Storage
At Parand Darou Co., Morphine Base is processed and purified under rigorous Quality Control (QC) supervision, adhering to strict In-house Specifications with a minimum chemical purity of 99.0%. Due to its photosensitivity, the product must be stored in light-protected containers. Its chemical integrity is guaranteed for at least 2 years when stored at room temperature.
General Information
| Product Name | Morphine Base | |
| Chemical Name | (4R,4aR,7S,7aR,12bS)-3-Methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol | |
| Manufacturer | Parand Darou Co. | |
| CAS No. | 57-27-2 | |
| Pharmacopoeia | In-house |
Specification
| Molecular formula | C17H19NO3 | Melting point | 245-256 °C (dec.) | |||
| Molecular weight | 285.34 | Purity | Min 99.0% | |||
| Appearance | Creamy crystalline powder | Assay | Min 98.0% (anhydrous) | |||
| Solubility | Sparingly sol. in Methanol | Storage | Protected from light | |||
| Water | Max 6.5% | Stability | 2 years at RT |
