Oxymorphone HCl (Oxymorphone Hydrochloride) is a potent semi-synthetic opioid analgesic used extensively in pain management. This Active Pharmaceutical Ingredient (API) is manufactured at Parand Darou Pharmaceutical Company using advanced technologies under stringent quality control, in full compliance with United States Pharmacopeia (USP) standards.
Mechanism of Action & Therapeutic Application
Oxymorphone exerts its analgesic effect by binding specifically and agonistically to μ-opioid receptors in the central nervous system, effectively inhibiting pain signal transmission. This vital medication is primarily indicated for the relief of moderate-to-severe acute pain, chronic cancer pain, and conditions where other analgesics are ineffective. Parand Darou’s Oxymorphone HCl is produced with a precise assay of 97.0% to 102.0% (dried basis) to ensure optimal therapeutic efficacy.
Physicochemical Properties & Storage
Oxymorphone HCl is supplied as an odorless, white or slightly off-white powder. It exhibits high solubility in water and is sparingly soluble in alcohol and ether. The specific optical rotation ranges from -145° to -155°, with a chloride content between 10.2% and 10.8%. To maintain stability for at least 2 years at room temperature, it must be stored in tight, light-resistant containers at 25°C (with permitted excursions between 15°C and 30°C).
General Information
| Product Name | Oxymorphone HCl | |
| Chemical Name | 4,5α-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride | |
| Manufacturer | Parand Darou Co. | |
| CAS No. | 357-07-3 | |
| Category | Pain management | |
| Pharmacopoeia | USP |
Specification
| Molecular formula | C17H19NO4.HCl | Chloride content | 10.2%–10.8% (dried) | |||
| Molecular weight | 337.8 | Residue on ignition | Max. 0.3% | |||
| Appearance | White or off-white, odorless powder | Assay | 97.0%–102.0% (dried) | |||
| Solubility | Freely soluble in water; sparingly soluble in alcohol and ether | Storage | Tight, light-resistant containers. 25°C (15–30°C) | |||
| Water | Max. 8.0% | Stability | Stable at least 2 years at R.T | |||
| Optical rotation | -145° to -155° |
