Papaverine Hydrochloride
| Grade | Pharmaceutical |
| Pharmacopoeia | USP, BP |
| CAS No. | 61-25-6 |
| Product Name | Papaverine Hydrochloride |
| Chemical Name | 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride |
| Function | Active Pharmaceutical Ingredients (APIs) |
| Industrial Application | Pharmaceutical |
| Category | Antispasmodic |
General Description
Papaverine Hydrochloride is a phosphodiesterase inhibitor and smooth muscle relaxant. It is an opium alkaloid antispasmodic drug, used primarily in the treatment of visceral spasms and vasospasms, and occasionally in the treatment of erectile dysfunction and acute mesenteric ischemia.
Physical Characteristics
| Molecular formula | C₂₀H₂₂ClNO₄ |
| Molecular weight | 375.9 |
| Appearance | White or almost white, crystalline powder, or white or almost white crystals |
| Solubility | Sparingly soluble in water, slightly soluble in ethanol |
| Melting point | 146 – 149 °C |
| pH | 3.0 – 4.5 |
| Water | Maximum 0.5% (105 °C) |
| Sulfated ash | Maximum 0.1% |
| Purity | Minimum 99.5% |
| Assay | 99.0% to 101.0% (dried substance) |
| Storage | Preserve in tight, light-resistant |