Oxycodone Hydrochloride
| Grade |
Pharmaceutical |
| Pharmacopoeia |
USP, BP |
| CAS No. |
124-90-3 |
| Product Name |
Oxycodone Hydrochloride |
| Chemical Name |
4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride |
| Function |
Active Pharmaceutical Ingredients (APIs) |
| Industrial Application |
Pharmaceutical |
| Category |
Pain management |
General Description
Opioids are natural and synthetic compositions which target the mu, kappa, and delta endogenous opioid receptors.
Endogenous peptides employ pain relief intermediatory acts on these receptors.
Opioids mimic the peptide effect on these receptors.
Intensity of pain, route of administration, and duration of patient usage are suitable criteria for selecting the appropriate opioid.
Oxycodone, a semi-synthetic opioid, is used medically for treatment of moderate to severe pain, and also has non-analgesic effects on the respiratory system.
It is also known as a cough suppressant.
Physical Characteristics
| Molecular formula |
C₁₈H₂₂ClNO₄ |
| Molecular weight |
351.82 |
| Appearance |
White or almost white powder, hygroscopic |
| Solubility |
Freely soluble in water, sparingly soluble in anhydrous ethanol, practically insoluble in toluene |
| Water |
Maximum 7.0% |
| Residue on ignition |
Maximum 0.05% |
| Specific optical rotation |
Between -140 to -148 |
| Sulfated ash |
Maximum 0.1% |
| Ethanol |
Maximum 1.0% |
| Purity |
Minimum 98.5% |
| Assay |
98.5% to 101.5% (dried substance) |
| Storage |
In airtight containers, protected from light |
| Stability |
Stable at least 2 years at room temperature |
