Dihydrocodeine Phosphate
| Grade | Pharmaceutical |
| Pharmacopoeia | JP |
| CAS No. | 24204-13-5 |
| Product Name | Dihydrocodeine Phosphate |
| Chemical Name | (5R,6S)-4,5-Epoxy-3-methoxy-17-methylmorphinan-6-ol monophosphate |
| Function | Active Pharmaceutical Ingredients (APIs) |
| Industrial Application | Pharmaceutical |
| Category | Pain management |
General Description
Dihydrocodeine phosphate is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.
Physical Characteristics
| Molecular formula | C₁₈H₂₃NO₃·H₃PO₄ |
| Molecular weight | 399.38 |
| Appearance | White to yellowish white crystalline powder |
| Solubility | Freely soluble in water and in acetic acid (100), slightly soluble in ethanol (95%), practically insoluble in diethyl ether |
| pH | Between 3.0 and 5.0 |
| Chloride | Maximum 0.021% |
| Sulfate | Maximum 0.024% |
| Water | Maximum 1.0% (105 °C) |
| Assay | Minimum 98.0% (dried basis) |
| Storage | Containers: Tight containers. Storage: Light-resistant |
| Stability | Stable at least 2 years at room temperature |