Buprenorphine Hydrochloride
| Grade | Pharmaceutical |
| Pharmacopoeia | BP, USP, IP |
| CAS No. | 53152-21-9 |
| Product Name | Buprenorphine Hydrochloride |
| Chemical Name | (2S)-2-[17-(Cyclopropylmethyl)-4,5α-epoxy-3-hydroxy-6-methoxy-6α,14-ethano-14α-morphinan-7α-yl]-3,3-dimethylbutan-2-ol hydrochloride |
| Function | Active Pharmaceutical Ingredients (APIs) |
| Industrial Application | Pharmaceutical |
| Category | Addiction therapy |
General Description
Buprenorphine is an opioid antagonist which is used mainly for opioid addiction to reduce cravings and withdrawal symptoms without causing euphoria or dangerous side effects, and helps prevent relapse with minimal discomfort.
Physical Characteristics
| Molecular formula | C₂₉H₄₂ClNO₄ |
| Molecular weight | 504.1 |
| Appearance | White or almost white, crystalline powder |
| Solubility | Sparingly soluble in water, freely soluble in methanol, soluble in ethanol (96%), practically insoluble in cyclohexane |
| Heavy metals | Maximum 20 ppm |
| Water | Maximum 1.0% |
| Specific optical rotation | -92 to -98 (dried substance) |
| Sulfated ash | Maximum 0.2% |
| Purity | Minimum 99.3% |
| Assay | 98.5% to 101.5% (dried substance) |
| Storage | Protected from light |
| Stability | Stable at least 2 years at room temperature |