{"id":1623,"date":"2025-06-08T11:56:51","date_gmt":"2025-06-08T11:56:51","guid":{"rendered":"https:\/\/paranddarou.co\/?p=1623"},"modified":"2025-06-09T05:19:04","modified_gmt":"2025-06-09T05:19:04","slug":"dapagliflozin-propanediol","status":"publish","type":"post","link":"https:\/\/paranddarou.co\/index.php\/2025\/06\/08\/dapagliflozin-propanediol\/","title":{"rendered":"Dapagliflozin Propanediol"},"content":{"rendered":"

Dapagliflozin Propanediol<\/span><\/h2>\n\n\n\n\n\n\n\n\n\n\n
Grade<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Pharmacopoeia<\/strong><\/td>\nUSP<\/td>\n<\/tr>\n
CAS No.<\/strong><\/td>\n960404-48-2<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\nDapagliflozin Propanediol<\/td>\n<\/tr>\n
Chemical Name<\/strong><\/td>\n(2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (S)-propane-1,2-diol (1:1) monohydrate<\/td>\n<\/tr>\n
Function<\/strong><\/td>\nActive Pharmaceutical Ingredients (APIs)<\/td>\n<\/tr>\n
Industrial Application<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Category<\/strong><\/td>\nAntidiabetic type 2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

General Description<\/span><\/h3>\n

Dapagliflozin is used to treat type 2 diabetes. It is also prescribed for adults with heart failure and chronic kidney disease. This compound reversibly inhibits sodium-glucose co-transporter 2 (SGLT-2) in the renal proximal convoluted tubule, reducing glucose reabsorption and increasing urinary glucose excretion.<\/p>\n

Physical Characteristics<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n
Molecular formula<\/strong><\/td>\nC\u2082\u2081H\u2082\u2085ClO\u2086\u00b7C\u2083H\u2088O\u2082\u00b7H\u2082O<\/td>\n<\/tr>\n
Molecular weight<\/strong><\/td>\n502.99<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite or off white, crystalline powder<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nFreely soluble in methanol, soluble in acetonitrile, very slightly soluble in water<\/td>\n<\/tr>\n
Water<\/strong><\/td>\n3.2% \u2013 4.0%<\/td>\n<\/tr>\n
Content of propanediol<\/strong><\/td>\n14.0% \u2013 16.5%<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\nMinimum 99.7%<\/td>\n<\/tr>\n
Assay<\/strong><\/td>\n98.0% to 102.0% (anhydrous, propanediol-free, and solvent-free basis)<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nPreserve in a well-closed container. Store at controlled room temperature<\/td>\n<\/tr>\n
Stability<\/strong><\/td>\nStable at least 2 years at room temperature<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Dapagliflozin Propanediol Grade Pharmaceutical Pharmacopoeia USP CAS No. 960404-48-2 Product Name Dapagliflozin Propanediol Chemical Name (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (S)-propane-1,2-diol (1:1) monohydrate Function Active Pharmaceutical Ingredients (APIs) Industrial Application Pharmaceutical Category Antidiabetic type 2 General Description Dapagliflozin is used to treat type 2 diabetes. It is also prescribed for adults with heart failure and chronic kidney disease. This […]<\/p>\n","protected":false},"author":1,"featured_media":970,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[137],"class_list":["post-1623","post","type-post","status-publish","format-standard","has-post-thumbnail","category-api","tag-dapagliflozin-is-used-to-treat-type-2-diabetes-it-is-also-prescribed-for-adults-with-heart-failure-and-chronic-kidney-disease"],"_links":{"self":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1623","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/comments?post=1623"}],"version-history":[{"count":3,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1623\/revisions"}],"predecessor-version":[{"id":1708,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1623\/revisions\/1708"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media\/970"}],"wp:attachment":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media?parent=1623"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/categories?post=1623"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/tags?post=1623"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}