{"id":1621,"date":"2025-06-08T11:55:25","date_gmt":"2025-06-08T11:55:25","guid":{"rendered":"https:\/\/paranddarou.co\/?p=1621"},"modified":"2025-06-09T05:20:16","modified_gmt":"2025-06-09T05:20:16","slug":"sitagliptin-phosphate","status":"publish","type":"post","link":"https:\/\/paranddarou.co\/index.php\/2025\/06\/08\/sitagliptin-phosphate\/","title":{"rendered":"Sitagliptin Phosphate"},"content":{"rendered":"

Sitagliptin Phosphate<\/span><\/h2>\n\n\n\n\n\n\n\n\n\n\n
Grade<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Pharmacopoeia<\/strong><\/td>\nUSP, BP<\/td>\n<\/tr>\n
CAS No.<\/strong><\/td>\n654671-77-9<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\nSitagliptin Phosphate<\/td>\n<\/tr>\n
Chemical Name<\/strong><\/td>\n(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-\u03b1]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate<\/td>\n<\/tr>\n
Function<\/strong><\/td>\nActive Pharmaceutical Ingredients (APIs)<\/td>\n<\/tr>\n
Industrial Application<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Category<\/strong><\/td>\nAntidiabetic type 2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

General Description<\/span><\/h3>\n

Sitagliptin lowers blood glucose in type 2 diabetes. It belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. Sitagliptin improves glycemic control by increasing the levels of incretin hormones, thereby stimulating insulin release and reducing glucagon secretion.<\/p>\n

Physical Characteristics<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Molecular formula<\/strong><\/td>\nC\u2081\u2086H\u2082\u2080F\u2086N\u2085O\u2086P<\/td>\n<\/tr>\n
Molecular weight<\/strong><\/td>\n523.32<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite or almost white powder<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nSoluble in water, very slightly soluble in anhydrous ethanol, practically insoluble in heptane<\/td>\n<\/tr>\n
Water<\/strong><\/td>\n3.3% to 3.7%<\/td>\n<\/tr>\n
Sulfated ash<\/strong><\/td>\nMaximum 0.2%<\/td>\n<\/tr>\n
Enantiomeric purity<\/strong><\/td>\nImpurity A: Maximum 0.50%; Reporting threshold: 0.1%<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\nMinimum 99.5%<\/td>\n<\/tr>\n
Assay<\/strong><\/td>\n98.0% to 102.0% (dried substance)<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nPreserve in a well-closed container. Store at controlled room temperature<\/td>\n<\/tr>\n
Stability<\/strong><\/td>\nStable at least 2 years at room temperature<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Sitagliptin Phosphate Grade Pharmaceutical Pharmacopoeia USP, BP CAS No. 654671-77-9 Product Name Sitagliptin Phosphate Chemical Name (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-\u03b1]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate Function Active Pharmaceutical Ingredients (APIs) Industrial Application Pharmaceutical Category Antidiabetic type 2 General Description Sitagliptin lowers blood glucose in type 2 diabetes. It belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. Sitagliptin improves […]<\/p>\n","protected":false},"author":1,"featured_media":970,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-1621","post","type-post","status-publish","format-standard","has-post-thumbnail","category-api"],"_links":{"self":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/comments?post=1621"}],"version-history":[{"count":3,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1621\/revisions"}],"predecessor-version":[{"id":1710,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1621\/revisions\/1710"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media\/970"}],"wp:attachment":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media?parent=1621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/categories?post=1621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/tags?post=1621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}