{"id":1593,"date":"2025-06-08T07:49:27","date_gmt":"2025-06-08T07:49:27","guid":{"rendered":"https:\/\/paranddarou.co\/?p=1593"},"modified":"2025-06-09T06:37:13","modified_gmt":"2025-06-09T06:37:13","slug":"naloxone-hydrochloride","status":"publish","type":"post","link":"https:\/\/paranddarou.co\/index.php\/2025\/06\/08\/naloxone-hydrochloride\/","title":{"rendered":"Naloxone Hydrochloride"},"content":{"rendered":"

Naloxone Hydrochloride<\/span><\/h2>\n\n\n\n\n\n\n\n\n\n\n
Grade<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Pharmacopoeia<\/strong><\/td>\nBP, USP<\/td>\n<\/tr>\n
CAS No.<\/strong><\/td>\n51481-60-8<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\nNaloxone Hydrochloride<\/td>\n<\/tr>\n
Chemical Name<\/strong><\/td>\n4,5\u03b1-Epoxy-3,14-dihydroxy-17-(prop-2-enyl)morphinan-6-one hydrochloride dihydrate<\/td>\n<\/tr>\n
Function<\/strong><\/td>\nActive Pharmaceutical Ingredients (APIs)<\/td>\n<\/tr>\n
Industrial Application<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Category<\/strong><\/td>\nOpioid overdose antidote<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

General Description<\/span><\/h3>\n

Naloxone is an FDA-approved medicine used to quickly reverse an opioid overdose. It is an opioid antagonist used in opioid use disorder. Naloxone works by blocking the opioid receptors and thereby reverses and blocks the effects of other opioids. It should be used as soon as possible to treat a known or suspected overdose. Naloxone is a synthetic cogener of oxymorphone.<\/p>\n

Physical Characteristics<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Molecular formula<\/strong><\/td>\nC\u2081\u2089H\u2082\u2082ClNO\u2084\u00b72H\u2082O<\/td>\n<\/tr>\n
Molecular weight<\/strong><\/td>\n399.9<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite or almost white, hygroscopic, crystalline powder<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nFreely soluble in water, soluble in ethanol (96%), practically insoluble in toluene<\/td>\n<\/tr>\n
Water<\/strong><\/td>\n7.5% to 11.0%<\/td>\n<\/tr>\n
Specific optical rotation<\/strong><\/td>\n-181 to -170 (anhydrous substance)<\/td>\n<\/tr>\n
Sulfated ash<\/strong><\/td>\nMaximum 0.2%<\/td>\n<\/tr>\n
Content of chloride<\/strong><\/td>\n9.54%\u20139.94% (on dried basis)<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\nMinimum 99.2%<\/td>\n<\/tr>\n
Assay<\/strong><\/td>\n98.0% to 102.0% (anhydrous substance)<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nIn an airtight container, protected from light<\/td>\n<\/tr>\n
Stability<\/strong><\/td>\nStable at least 2 years at room temperature<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Naloxone Hydrochloride Grade Pharmaceutical Pharmacopoeia BP, USP CAS No. 51481-60-8 Product Name Naloxone Hydrochloride Chemical Name 4,5\u03b1-Epoxy-3,14-dihydroxy-17-(prop-2-enyl)morphinan-6-one hydrochloride dihydrate Function Active Pharmaceutical Ingredients (APIs) Industrial Application Pharmaceutical Category Opioid overdose antidote General Description Naloxone is an FDA-approved medicine used to quickly reverse an opioid overdose. It is an opioid antagonist used in opioid use disorder. […]<\/p>\n","protected":false},"author":1,"featured_media":970,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[123],"class_list":["post-1593","post","type-post","status-publish","format-standard","has-post-thumbnail","category-api","tag-naloxone-hydrochloride"],"_links":{"self":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1593","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/comments?post=1593"}],"version-history":[{"count":3,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1593\/revisions"}],"predecessor-version":[{"id":1738,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1593\/revisions\/1738"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media\/970"}],"wp:attachment":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media?parent=1593"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/categories?post=1593"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/tags?post=1593"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}