{"id":1581,"date":"2025-06-08T07:38:39","date_gmt":"2025-06-08T07:38:39","guid":{"rendered":"https:\/\/paranddarou.co\/?p=1581"},"modified":"2025-06-08T07:38:39","modified_gmt":"2025-06-08T07:38:39","slug":"methadone-hydrochloride","status":"publish","type":"post","link":"https:\/\/paranddarou.co\/index.php\/2025\/06\/08\/methadone-hydrochloride\/","title":{"rendered":"Methadone Hydrochloride"},"content":{"rendered":"

Methadone Hydrochloride<\/span><\/h2>\n\n\n\n\n\n\n\n\n\n\n
Grade<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Pharmacopoeia<\/strong><\/td>\nUSP, BP<\/td>\n<\/tr>\n
CAS No.<\/strong><\/td>\n1095-90-5<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\nMethadone Hydrochloride<\/td>\n<\/tr>\n
Chemical Name<\/strong><\/td>\n(6RS)-6-(Dimethylamino)-4,4-diphenylheptan-3-one hydrochloride<\/td>\n<\/tr>\n
Function<\/strong><\/td>\nActive Pharmaceutical Ingredients (APIs)<\/td>\n<\/tr>\n
Industrial Application<\/strong><\/td>\nPharmaceutical<\/td>\n<\/tr>\n
Category<\/strong><\/td>\nAddiction therapy<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

General Description<\/span><\/h3>\n

Methadone is a synthetic opioid which is the major drug used in addiction therapy and maintenance therapy.
\nMethadone has no metabolite. Its plasma concentration lasts 6\u20138 hours and increases on extended use.
\nIts onset effect is within 0.5\u20131 hour and lasts for 12 hours on extended use.
\nIts unique crystalline form is an added value in the manufacturing process.<\/p>\n

Physical Characteristics<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Molecular formula<\/strong><\/td>\nC\u2082\u2081H\u2082\u2088ClNO<\/td>\n<\/tr>\n
Molecular weight<\/strong><\/td>\n345.9<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite or almost white, crystalline powder<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nSoluble in water, freely soluble in ethanol (96%)<\/td>\n<\/tr>\n
Melting point<\/strong><\/td>\n233 – 236 \u00b0C<\/td>\n<\/tr>\n
pH<\/strong><\/td>\n4.5 – 6.5<\/td>\n<\/tr>\n
Water content<\/strong><\/td>\nMaximum 0.5% (105 \u00b0C)<\/td>\n<\/tr>\n
Optical rotation<\/strong><\/td>\nBetween -0.05\u00b0 to +0.05\u00b0<\/td>\n<\/tr>\n
Sulfated ash<\/strong><\/td>\nMaximum 0.1%<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\nMinimum 99.7%<\/td>\n<\/tr>\n
Assay<\/strong><\/td>\n99.0% to 101.0% (dried substance)<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nProtected from light<\/td>\n<\/tr>\n
Stability<\/strong><\/td>\nStable at least 2 years at room temperature<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Methadone Hydrochloride Grade Pharmaceutical Pharmacopoeia USP, BP CAS No. 1095-90-5 Product Name Methadone Hydrochloride Chemical Name (6RS)-6-(Dimethylamino)-4,4-diphenylheptan-3-one hydrochloride Function Active Pharmaceutical Ingredients (APIs) Industrial Application Pharmaceutical Category Addiction therapy General Description Methadone is a synthetic opioid which is the major drug used in addiction therapy and maintenance therapy. Methadone has no metabolite. Its plasma concentration […]<\/p>\n","protected":false},"author":1,"featured_media":970,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[117],"class_list":["post-1581","post","type-post","status-publish","format-standard","has-post-thumbnail","category-api","tag-methadone-is-a-synthetic-opioid-which-is-the-major-drug-used-in-addiction-therapy-and-maintenance-therapy-methadone-has-no-metabolite"],"_links":{"self":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1581","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/comments?post=1581"}],"version-history":[{"count":1,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1581\/revisions"}],"predecessor-version":[{"id":1582,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/posts\/1581\/revisions\/1582"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media\/970"}],"wp:attachment":[{"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/media?parent=1581"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/categories?post=1581"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paranddarou.co\/index.php\/wp-json\/wp\/v2\/tags?post=1581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}