Codeine Anhydrous

Codeine Anhydrous

Grade Pharmaceutical
Pharmacopoeia USP
CAS No. 76-57-3
Product Name Codeine Anhydrous
Chemical Name 4,5α-Epoxy-3-methoxy-17-methyl-7,8-didehydromorphinan-6α-ol
Function Intermediate
Industrial Applications Pharmaceutical
Category Pain management

General Description

Codeine is derived from the poppy plant, Papaver somniferum (Papaveraceae). Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing. Codeine anhydrous is a precursor for synthesis of many opioid derivatives such as codeine phosphate.

Physical Characteristics

Molecular formula C18H21NO3
Molecular weight 299.37
Appearance White to off-white, slightly coloured solid
Solubility Soluble in boiling water, freely soluble in ethanol (96%)
Melting point 155 – 159 °C
Water Maximum 2.0%
Sulfate Maximum 0.4%
Purity Minimum 97.0%
Assay Minimum 97.0%
Storage Protected from light
Stability Stable at least 2 years at R.T

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