{"id":381,"date":"2026-09-16T17:19:20","date_gmt":"2026-09-16T13:49:20","guid":{"rendered":"https:\/\/paranddarou.co\/Fa\/?p=381"},"modified":"2026-09-16T17:19:20","modified_gmt":"2026-09-16T13:49:20","slug":"%da%a9%d8%af%d8%a6%db%8c%d9%86-%d9%81%d8%b3%d9%81%d8%a7%d8%aa-%d9%87%d9%85%db%8c%d9%87%db%8c%d8%af%d8%b1%d8%a7%d8%aa-codeine-phosphate-hemihydrate","status":"publish","type":"post","link":"https:\/\/paranddarou.co\/Fa\/?p=381","title":{"rendered":"\u06a9\u062f\u0626\u06cc\u0646 \u0641\u0633\u0641\u0627\u062a \u0647\u0645\u06cc\u200c\u0647\u06cc\u062f\u0631\u0627\u062a (Codeine Phosphate Hemihydrate)"},"content":{"rendered":"

<\/p>\n

\n

\u06a9\u062f\u0626\u06cc\u0646 \u0641\u0633\u0641\u0627\u062a \u0647\u0645\u06cc\u200c\u0647\u06cc\u062f\u0631\u0627\u062a (Codeine Phosphate Hemihydrate)<\/strong> \u0627\u0632 \u0645\u0634\u062a\u0642\u0627\u062a \u0627\u0648\u067e\u06cc\u0648\u0626\u06cc\u062f\u06cc \u0648 \u06cc\u06a9\u06cc \u0627\u0632 \u067e\u0631\u06a9\u0627\u0631\u0628\u0631\u062f\u062a\u0631\u06cc\u0646 \u0645\u0648\u0627\u062f \u0645\u0624\u062b\u0631\u0647 \u062f\u0627\u0631\u0648\u06cc\u06cc (API) \u0636\u062f \u062f\u0631\u062f \u0648 \u0636\u062f \u0633\u0631\u0641\u0647 \u062f\u0631 \u062c\u0647\u0627\u0646 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0631 \u0634\u0631\u06a9\u062a \u062f\u0627\u0631\u0648\u0633\u0627\u0632\u06cc \u067e\u0631\u0646\u062f \u062f\u0627\u0631\u0648<\/strong> \u062a\u062d\u062a \u0636\u0648\u0627\u0628\u0637 \u062f\u0642\u06cc\u0642 GMP \u0648 \u0645\u0637\u0627\u0628\u0642 \u0628\u0627 \u0622\u062e\u0631\u06cc\u0646 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u0647\u0627\u06cc \u0641\u0627\u0631\u0645\u0627\u06a9\u0648\u067e\u0647\u200c\u0627\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc (USP \u0648 BP) \u0633\u0646\u062a\u0632 \u0648 \u0641\u0631\u0622\u0648\u0631\u06cc \u0645\u06cc\u200c\u0634\u0648\u062f. \u0627\u06cc\u0646 \u0646\u0645\u06a9 \u0641\u0633\u0641\u0627\u062a \u0628\u0647 \u062f\u0644\u06cc\u0644 \u0627\u0646\u062d\u0644\u0627\u0644\u200c\u067e\u0630\u06cc\u0631\u06cc \u0628\u0633\u06cc\u0627\u0631 \u0628\u0627\u0644\u0627 \u062f\u0631 \u0622\u0628\u060c \u0645\u0627\u062f\u0647 \u067e\u0627\u06cc\u0647 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644\u06cc \u062f\u0631 \u0641\u0631\u0645\u0648\u0644\u0627\u0633\u06cc\u0648\u0646 \u0627\u0646\u0648\u0627\u0639 \u0642\u0631\u0635\u200c\u0647\u0627\u06cc \u0645\u0633\u06a9\u0646 \u062a\u0631\u06a9\u06cc\u0628\u06cc\u060c \u0634\u0631\u0628\u062a\u200c\u0647\u0627 \u0648 \u0645\u062d\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u062e\u0648\u0631\u0627\u06a9\u06cc \u0628\u0647 \u0634\u0645\u0627\u0631 \u0645\u06cc\u200c\u0631\u0648\u062f.<\/p>\n

\u0645\u06a9\u0627\u0646\u06cc\u0633\u0645 \u0627\u062b\u0631 \u0648 \u06a9\u0627\u0631\u0628\u0631\u062f\u0647\u0627\u06cc \u062f\u0631\u0645\u0627\u0646\u06cc \u06a9\u062f\u0626\u06cc\u0646 \u0641\u0633\u0641\u0627\u062a<\/h3>\n

\u06a9\u062f\u0626\u06cc\u0646 \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u06cc\u06a9 \u0622\u06af\u0648\u0646\u06cc\u0633\u062a \u0627\u0646\u062a\u062e\u0627\u0628\u06cc \u06af\u06cc\u0631\u0646\u062f\u0647\u200c\u0647\u0627\u06cc \u0645\u0648-\u0627\u0648\u067e\u06cc\u0648\u0626\u06cc\u062f\u06cc (\u00b5-opioid receptors) \u0639\u0645\u0644 \u06a9\u0631\u062f\u0647 \u0648 \u067e\u0633 \u0627\u0632 \u062a\u0628\u062f\u06cc\u0644 \u0628\u0647 \u0645\u0648\u0631\u0641\u06cc\u0646 \u062f\u0631 \u06a9\u0628\u062f\u060c \u0628\u0627 \u0645\u0647\u0627\u0631 \u0627\u0646\u062a\u0642\u0627\u0644 \u0633\u06cc\u06af\u0646\u0627\u0644\u200c\u0647\u0627\u06cc \u062f\u0631\u062f \u062f\u0631 \u0633\u06cc\u0633\u062a\u0645 \u0627\u0639\u0635\u0627\u0628 \u0645\u0631\u06a9\u0632\u06cc\u060c \u0627\u062b\u0631 \u0636\u062f \u062f\u0631\u062f\u06cc (Analgesic) \u062e\u0648\u062f \u0631\u0627 \u0627\u0639\u0645\u0627\u0644 \u0645\u06cc\u200c\u06a9\u0646\u062f. \u0647\u0645\u0686\u0646\u06cc\u0646 \u0628\u0627 \u0645\u0647\u0627\u0631 \u0645\u0633\u062a\u0642\u06cc\u0645 \u0645\u0631\u06a9\u0632 \u0631\u0641\u0644\u06a9\u0633 \u0633\u0631\u0641\u0647 \u062f\u0631 \u0628\u0635\u0644\u200c\u0627\u0644\u0646\u062e\u0627\u0639\u060c \u062f\u0631 \u06a9\u0646\u062a\u0631\u0644 \u0648 \u062a\u0633\u06a9\u06cc\u0646 \u0633\u0631\u0641\u0647\u200c\u0647\u0627\u06cc \u062e\u0634\u06a9 \u0648 \u062f\u0631\u062f\u0646\u0627\u06a9 \u0628\u0633\u06cc\u0627\u0631 \u0645\u0624\u062b\u0631 \u0627\u0633\u062a. \u0627\u0632 \u0627\u06cc\u0646 \u0645\u0627\u062f\u0647 \u0645\u0624\u062b\u0631\u0647 \u062f\u0631 \u0627\u0634\u06a9\u0627\u0644 \u062f\u0627\u0631\u0648\u06cc\u06cc \u062a\u0644\u0641\u06cc\u0642\u06cc (\u0646\u0638\u06cc\u0631 \u062a\u0631\u06a9\u06cc\u0628 \u0628\u0627 \u0627\u0633\u062a\u0627\u0645\u06cc\u0646\u0648\u0641\u0646\u060c \u0627\u06cc\u0628\u0648\u067e\u0631\u0648\u0641\u0646 \u0648 \u0622\u0646\u062a\u06cc\u200c\u0647\u06cc\u0633\u062a\u0627\u0645\u06cc\u0646\u200c\u0647\u0627) \u062c\u0647\u062a \u0645\u062f\u06cc\u0631\u06cc\u062a \u062f\u0631\u062f\u0647\u0627\u06cc \u062e\u0641\u06cc\u0641 \u062a\u0627 \u0645\u062a\u0648\u0633\u0637 \u0648 \u0633\u0631\u06a9\u0648\u0628 \u0633\u0631\u0641\u0647 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/p>\n

\u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u0641\u06cc\u0632\u06cc\u06a9\u0648\u0634\u06cc\u0645\u06cc\u0627\u06cc\u06cc\u060c \u062e\u0644\u0648\u0635 \u0648 \u067e\u0627\u06cc\u062f\u0627\u0631\u06cc<\/h3>\n

\u0645\u0627\u062f\u0647 \u0645\u0624\u062b\u0631\u0647 \u06a9\u062f\u0626\u06cc\u0646 \u0641\u0633\u0641\u0627\u062a \u0647\u0645\u06cc\u200c\u0647\u06cc\u062f\u0631\u0627\u062a<\/strong> \u062a\u0648\u0644\u06cc\u062f\u06cc \u067e\u0631\u0646\u062f \u062f\u0627\u0631\u0648 \u0628\u0647 \u0635\u0648\u0631\u062a \u067e\u0648\u062f\u0631 \u06a9\u0631\u06cc\u0633\u062a\u0627\u0644\u06cc \u0633\u0641\u06cc\u062f \u06cc\u0627 \u0628\u0644\u0648\u0631\u0647\u0627\u06cc \u06a9\u0648\u0686\u06a9 \u0628\u06cc\u200c\u0631\u0646\u06af \u0628\u0627 \u062f\u0631\u062c\u0647 \u062e\u0644\u0648\u0635 \u062d\u062f\u0627\u0642\u0644 \u06f9\u06f8.\u06f0\u066a \u0648 \u0633\u0646\u062c\u0634 \u062e\u0644\u0648\u0635 (Assay) \u062f\u0631 \u0628\u0627\u0632\u0647 \u06f9\u06f8.\u06f5\u066a \u062a\u0627 \u06f1\u06f0\u06f1.\u06f0\u066a (\u0628\u0631 \u067e\u0627\u06cc\u0647 \u0645\u0627\u062f\u0647 \u062e\u0634\u06a9) \u0639\u0631\u0636\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f. \u0627\u06cc\u0646 \u062a\u0631\u06a9\u06cc\u0628 \u0628\u0627 \u0631\u0637\u0648\u0628\u062a \u06a9\u0645\u062a\u0631 \u0627\u0632 \u06f3.\u06f0\u066a \u0648 \u0645\u062d\u062f\u0648\u062f\u0647 pH \u0628\u06cc\u0646 \u06f4.\u06f0 \u062a\u0627 \u06f5.\u06f0\u060c \u067e\u0627\u06cc\u062f\u0627\u0631\u06cc \u0628\u0633\u06cc\u0627\u0631 \u0628\u0627\u0644\u0627\u06cc\u06cc (\u062d\u062f\u0627\u0642\u0644 \u06f2 \u0633\u0627\u0644 \u062f\u0631 \u062f\u0645\u0627\u06cc \u0627\u062a\u0627\u0642) \u062f\u0627\u0631\u062f \u0648 \u0628\u0627\u06cc\u062f \u062f\u0631 \u0634\u0631\u0627\u06cc\u0637 \u0645\u062d\u0641\u0648\u0638 \u0627\u0632 \u0646\u0648\u0631 \u0648 \u062f\u0631 \u0628\u0633\u062a\u0647\u200c\u0628\u0646\u062f\u06cc\u200c\u0647\u0627\u06cc \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u0646\u06af\u0647\u062f\u0627\u0631\u06cc \u0634\u0648\u062f.<\/p>\n<\/div>\n

<\/p>\n

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<\/p>\n

General Information<\/h3>\n\n\n\n\n\n\n\n\n
Product Name<\/td>\n<\/td>\nCodeine Phosphate Hemihydrate<\/td>\n<\/tr>\n
Chemical Name<\/td>\n<\/td>\n4,5\u03b1-Epoxy-3-methoxy-17-methyl-7,8-didehydromorphinan-6\u03b1-ol phosphate hemihydrate<\/td>\n<\/tr>\n
Manufacturer<\/td>\n<\/td>\nParand Darou Co.<\/td>\n<\/tr>\n
CAS No.<\/td>\n<\/td>\n41444-62-6<\/td>\n<\/tr>\n
Category<\/td>\n<\/td>\nAnalgesic, Pain management<\/td>\n<\/tr>\n
Pharmacopia<\/td>\n<\/td>\nUSP, BP<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>\n

Specification<\/h3>\n\n\n\n\n\n\n\n\n\n
Molecular formula<\/td>\n<\/td>\nC18<\/sub>H21<\/sub>NO3<\/sub>\u00b7H3<\/sub>PO4<\/sub>\u00b71\/2H2<\/sub>O<\/td>\n<\/td>\nChloride<\/td>\n<\/td>\nNo opalescence is produced immediately<\/td>\n<\/tr>\n
Molecular weight<\/td>\n<\/td>\n406.4<\/td>\n<\/td>\nSulfate<\/td>\n<\/td>\nMax. 0.1%<\/td>\n<\/tr>\n
Appearance<\/td>\n<\/td>\nWhite or almost white, crystalline powder or small, colourless crystals<\/td>\n<\/td>\nSpecific optical rotation<\/td>\n<\/td>\n-98 to -102 (dried substance)<\/td>\n<\/tr>\n
Solubility<\/td>\n<\/td>\nFreely soluble in water, slightly soluble or very slightly soluble in ethanol (96%)<\/td>\n<\/td>\nPurity<\/td>\n<\/td>\nMin. 98.0%<\/td>\n<\/tr>\n
Melting point<\/td>\n<\/td>\n155 – 159 \u00b0C<\/td>\n<\/td>\nAssay<\/td>\n<\/td>\n98.5% to 101.0% (anhydrous basis)<\/td>\n<\/tr>\n
pH<\/td>\n<\/td>\n4.0 – 5.0<\/td>\n<\/td>\nStorage<\/td>\n<\/td>\nProtected from light<\/td>\n<\/tr>\n
Water<\/td>\n<\/td>\n< 3.0%<\/td>\n<\/td>\nStability<\/td>\n<\/td>\nStable at least 2 years at R.T<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u06a9\u062f\u0626\u06cc\u0646 \u0641\u0633\u0641\u0627\u062a \u0647\u0645\u06cc\u200c\u0647\u06cc\u062f\u0631\u0627\u062a (Codeine Phosphate Hemihydrate) \u0627\u0632 \u0645\u0634\u062a\u0642\u0627\u062a \u0627\u0648\u067e\u06cc\u0648\u0626\u06cc\u062f\u06cc \u0648 \u06cc\u06a9\u06cc \u0627\u0632 \u067e\u0631\u06a9\u0627\u0631\u0628\u0631\u062f\u062a\u0631\u06cc\u0646 \u0645\u0648\u0627\u062f \u0645\u0624\u062b\u0631\u0647 \u062f\u0627\u0631\u0648\u06cc\u06cc (API) \u0636\u062f \u062f\u0631\u062f \u0648 \u0636\u062f \u0633\u0631\u0641\u0647 \u062f\u0631 \u062c\u0647\u0627\u0646 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0631 \u0634\u0631\u06a9\u062a \u062f\u0627\u0631\u0648\u0633\u0627\u0632\u06cc \u067e\u0631\u0646\u062f \u062f\u0627\u0631\u0648 \u062a\u062d\u062a \u0636\u0648\u0627\u0628\u0637 \u062f\u0642\u06cc\u0642 GMP \u0648 \u0645\u0637\u0627\u0628\u0642 \u0628\u0627 \u0622\u062e\u0631\u06cc\u0646 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u0647\u0627\u06cc \u0641\u0627\u0631\u0645\u0627\u06a9\u0648\u067e\u0647\u200c\u0627\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc (USP \u0648 BP) \u0633\u0646\u062a\u0632 \u0648 \u0641\u0631\u0622\u0648\u0631\u06cc \u0645\u06cc\u200c\u0634\u0648\u062f. \u0627\u06cc\u0646 \u0646\u0645\u06a9 \u0641\u0633\u0641\u0627\u062a \u0628\u0647 \u062f\u0644\u06cc\u0644 \u0627\u0646\u062d\u0644\u0627\u0644\u200c\u067e\u0630\u06cc\u0631\u06cc […]<\/p>\n","protected":false},"author":1,"featured_media":382,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","footnotes":""},"categories":[36],"tags":[58],"class_list":["post-381","post","type-post","status-publish","format-standard","has-post-thumbnail","category-36","tag----codeine-phosphate-hemihydrate"],"_links":{"self":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts\/381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=381"}],"version-history":[{"count":1,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts\/381\/revisions"}],"predecessor-version":[{"id":383,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts\/381\/revisions\/383"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/media\/382"}],"wp:attachment":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}