{"id":378,"date":"2026-09-16T17:17:28","date_gmt":"2026-09-16T13:47:28","guid":{"rendered":"https:\/\/paranddarou.co\/Fa\/?p=378"},"modified":"2026-09-16T17:17:28","modified_gmt":"2026-09-16T13:47:28","slug":"%d9%86%d9%88%d8%b3%da%a9%d8%a7%d9%be%db%8c%d9%86-%d8%a8%db%8c%d8%b3-noscapine","status":"publish","type":"post","link":"https:\/\/paranddarou.co\/Fa\/?p=378","title":{"rendered":"\u0646\u0648\u0633\u06a9\u0627\u067e\u06cc\u0646 \u0628\u06cc\u0633 (Noscapine)"},"content":{"rendered":"

<\/p>\n

\n

\u0646\u0648\u0633\u06a9\u0627\u067e\u06cc\u0646 \u0628\u06cc\u0633 (Noscapine)<\/strong> \u0627\u0632 \u0622\u0644\u06a9\u0627\u0644\u0648\u0626\u06cc\u062f\u0647\u0627\u06cc \u0637\u0628\u06cc\u0639\u06cc \u06af\u06cc\u0627\u0647 \u062e\u0634\u062e\u0627\u0634 \u0648 \u0645\u062a\u0639\u0644\u0642 \u0628\u0647 \u062f\u0633\u062a\u0647 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0636\u062f \u0633\u0631\u0641\u0647 (Antitussive) \u0627\u0633\u062a \u06a9\u0647 \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u0645\u0627\u062f\u0647 \u0645\u0624\u062b\u0631\u0647 \u062f\u0627\u0631\u0648\u06cc\u06cc (API) \u062f\u0631 \u0634\u0631\u06a9\u062a \u062f\u0627\u0631\u0648\u0633\u0627\u0632\u06cc \u067e\u0631\u0646\u062f \u062f\u0627\u0631\u0648<\/strong> \u062a\u062d\u062a \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u0647\u0627\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc \u0641\u0627\u0631\u0645\u0627\u06a9\u0648\u067e\u0647\u200c\u0627\u06cc (USP\u060c BP \u0648 JP) \u062a\u0648\u0644\u06cc\u062f \u0645\u06cc\u200c\u0634\u0648\u062f. \u0627\u06cc\u0646 \u062a\u0631\u06a9\u06cc\u0628 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0628\u0647 \u062f\u0644\u06cc\u0644 \u0633\u0627\u062e\u062a\u0627\u0631 \u0634\u06cc\u0645\u06cc\u0627\u06cc\u06cc \u0641\u062a\u0627\u0644\u06cc\u062f \u0627\u06cc\u0632\u0648\u06a9\u06cc\u0646\u0648\u0644\u06cc\u0646 (Phthalideisoquinoline)\u060c \u0641\u0627\u0642\u062f \u0627\u062b\u0631\u0627\u062a \u0645\u062e\u062f\u0631\u06cc\u060c \u0636\u062f \u062f\u0631\u062f\u06cc \u0648 \u0648\u0627\u0628\u0633\u062a\u06af\u06cc \u0628\u0648\u062f\u0647 \u0648 \u062f\u0631 \u0641\u0631\u0645\u0648\u0644\u0627\u0633\u06cc\u0648\u0646 \u0627\u0646\u0648\u0627\u0639 \u0627\u0634\u06a9\u0627\u0644 \u062f\u0627\u0631\u0648\u06cc\u06cc \u062c\u0627\u0645\u062f \u0648 \u0645\u0627\u06cc\u0639 \u062c\u0647\u062a \u062a\u0633\u06a9\u06cc\u0646 \u0633\u0631\u0641\u0647\u200c\u0647\u0627\u06cc \u063a\u06cc\u0631\u0645\u0648\u0644\u062f \u0648 \u062e\u0634\u06a9 \u06a9\u0627\u0631\u0628\u0631\u062f \u06af\u0633\u062a\u0631\u062f\u0647\u200c\u0627\u06cc \u062f\u0627\u0631\u062f.<\/p>\n

\u0645\u06a9\u0627\u0646\u06cc\u0633\u0645 \u0627\u062b\u0631 \u0648 \u0645\u0632\u0627\u06cc\u0627\u06cc \u0641\u0627\u0631\u0645\u0627\u06a9\u0648\u0644\u0648\u0698\u06cc\u06a9 \u0646\u0648\u0633\u06a9\u0627\u067e\u06cc\u0646<\/h3>\n

\u0646\u0648\u0633\u06a9\u0627\u067e\u06cc\u0646 \u0627\u062b\u0631 \u0645\u0647\u0627\u0631\u06a9\u0646\u0646\u062f\u0647 \u0633\u0631\u0641\u0647 \u062e\u0648\u062f \u0631\u0627 \u0639\u0645\u062f\u062a\u0627\u064b \u0627\u0632 \u0637\u0631\u06cc\u0642 \u0633\u0631\u06a9\u0648\u0628 \u0645\u0631\u06a9\u0632\u06cc \u0631\u0641\u0644\u06a9\u0633 \u0633\u0631\u0641\u0647 \u062f\u0631 \u0633\u0627\u0642\u0647 \u0645\u063a\u0632 \u0648 \u0647\u0645\u0686\u0646\u06cc\u0646 \u0627\u062b\u0631 \u0622\u06af\u0648\u0646\u06cc\u0633\u062a\u06cc \u0628\u0631 \u06af\u06cc\u0631\u0646\u062f\u0647\u200c\u0647\u0627\u06cc \u0633\u06cc\u06af\u0645\u0627 (Sigma Receptors) \u0627\u0639\u0645\u0627\u0644 \u0645\u06cc\u200c\u06a9\u0646\u062f. \u0627\u06cc\u0646 \u062a\u0631\u06a9\u06cc\u0628 \u0628\u062f\u0648\u0646 \u062a\u0623\u062b\u06cc\u0631 \u0645\u0646\u0641\u06cc \u0628\u0631 \u0645\u0631\u06a9\u0632 \u062a\u0646\u0641\u0633\u060c \u0645\u0627\u0646\u0639 \u0627\u0632 \u0627\u0646\u0642\u0628\u0627\u0636 \u0648 \u062a\u062d\u0631\u06cc\u06a9 \u0645\u062c\u0627\u0631\u06cc \u0647\u0648\u0627\u06cc\u06cc \u0634\u062f\u0647 \u0648 \u06af\u0632\u06cc\u0646\u0647\u200c\u0627\u06cc \u0628\u0633\u06cc\u0627\u0631 \u0627\u06cc\u0645\u0646 \u062f\u0631 \u0641\u0631\u0622\u0648\u0631\u062f\u0647\u200c\u0647\u0627\u06cc \u0636\u062f \u0633\u0631\u0641\u0647 \u0628\u0647 \u0634\u0645\u0627\u0631 \u0645\u06cc\u200c\u0631\u0648\u062f. \u0639\u0644\u0627\u0648\u0647 \u0628\u0631 \u06a9\u0627\u0631\u0628\u0631\u062f \u0636\u062f \u0633\u0631\u0641\u0647\u060c \u067e\u0698\u0648\u0647\u0634\u200c\u0647\u0627\u06cc \u0646\u0648\u06cc\u0646 \u0628\u0647 \u0628\u0631\u0631\u0633\u06cc \u0646\u0642\u0634 \u0646\u0648\u0633\u06a9\u0627\u067e\u06cc\u0646 \u062f\u0631 \u0645\u0647\u0627\u0631 \u062a\u0642\u0633\u06cc\u0645 \u0633\u0644\u0648\u0644\u06cc \u0627\u0632 \u0637\u0631\u06cc\u0642 \u0628\u0631\u0647\u0645\u200c\u06a9\u0646\u0634 \u0628\u0627 \u062a\u0648\u0628\u0648\u0644\u06cc\u0646\u200c\u0647\u0627 \u067e\u0631\u062f\u0627\u062e\u062a\u0647\u200c\u0627\u0646\u062f.<\/p>\n

\u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u0641\u06cc\u0632\u06cc\u06a9\u0648\u0634\u06cc\u0645\u06cc\u0627\u06cc\u06cc \u0648 \u06a9\u0646\u062a\u0631\u0644 \u06a9\u06cc\u0641\u06cc<\/h3>\n

\u0645\u0627\u062f\u0647 \u0645\u0624\u062b\u0631\u0647 \u0646\u0648\u0633\u06a9\u0627\u067e\u06cc\u0646<\/strong> \u062f\u0631 \u062e\u0637\u0648\u0637 \u062a\u0648\u0644\u06cc\u062f \u067e\u0631\u0646\u062f \u062f\u0627\u0631\u0648 \u0628\u0647 \u0635\u0648\u0631\u062a \u067e\u0648\u062f\u0631 \u06a9\u0631\u06cc\u0633\u062a\u0627\u0644\u06cc \u0633\u0641\u06cc\u062f \u06cc\u0627 \u0628\u0644\u0648\u0631\u0647\u0627\u06cc \u0628\u06cc\u200c\u0631\u0646\u06af \u0628\u0627 \u062e\u0644\u0648\u0635 \u0634\u06cc\u0645\u06cc\u0627\u06cc\u06cc \u062d\u062f\u0627\u0642\u0644 \u06f9\u06f9.\u06f0\u066a \u0648 \u0633\u0646\u062c\u0634 \u062e\u0644\u0648\u0635 (Assay) \u062f\u0631 \u0628\u0627\u0632\u0647 \u06f9\u06f9.\u06f0\u066a \u062a\u0627 \u06f1\u06f0\u06f1.\u06f0\u066a (\u0628\u0631 \u067e\u0627\u06cc\u0647 \u0645\u0627\u062f\u0647 \u062e\u0634\u06a9) \u0628\u0647 \u062f\u0633\u062a \u0645\u06cc\u200c\u0622\u06cc\u062f. \u0627\u06cc\u0646 \u0645\u062d\u0635\u0648\u0644 \u0628\u0627 \u0631\u0637\u0648\u0628\u062a \u06a9\u0646\u062a\u0631\u0644\u200c\u0634\u062f\u0647 \u0632\u06cc\u0631 \u06f1.\u06f0\u066a \u0648 \u067e\u0627\u06cc\u062f\u0627\u0631\u06cc \u062d\u062f\u0627\u0642\u0644 \u06f2 \u0633\u0627\u0644 \u062f\u0631 \u062f\u0645\u0627\u06cc \u0627\u062a\u0627\u0642\u060c \u0628\u0627\u06cc\u062f \u062f\u0631 \u0638\u0631\u0648\u0641 \u06a9\u0627\u0645\u0644\u0627\u064b \u062f\u0631\u0628\u0633\u062a\u0647 (Well-closed container) \u0648 \u062f\u0648\u0631 \u0627\u0632 \u0631\u0637\u0648\u0628\u062a \u0648 \u0646\u0648\u0631 \u0646\u06af\u0647\u062f\u0627\u0631\u06cc \u0634\u0648\u062f.<\/p>\n<\/div>\n

<\/p>\n

\n

<\/p>\n

General Information<\/h3>\n\n\n\n\n\n\n\n\n
Product Name<\/td>\n<\/td>\nNoscapine<\/td>\n<\/tr>\n
Chemical Name<\/td>\n<\/td>\n(3S)-6,7-Dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5-yl]isobenzofuran-1(3H)-one<\/td>\n<\/tr>\n
Manufacturer<\/td>\n<\/td>\nParand Darou Co.<\/td>\n<\/tr>\n
CAS No.<\/td>\n<\/td>\n128-62-1<\/td>\n<\/tr>\n
Category<\/td>\n<\/td>\nAntitussive<\/td>\n<\/tr>\n
Pharmacopia<\/td>\n<\/td>\nUSP, BP, JP<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>\n

Specification<\/h3>\n\n\n\n\n\n\n\n\n
Molecular formula<\/td>\n<\/td>\nC22<\/sub>H23<\/sub>NO7<\/sub><\/td>\n<\/td>\nSulfated ash<\/td>\n<\/td>\nMax. 0.1%<\/td>\n<\/tr>\n
Molecular weight<\/td>\n<\/td>\n413.43<\/td>\n<\/td>\nOptical rotation<\/td>\n<\/td>\n+42\u00b0 to +48\u00b0<\/td>\n<\/tr>\n
Appearance<\/td>\n<\/td>\nWhite or almost white, crystalline powder or colourless crystals<\/td>\n<\/td>\nPurity<\/td>\n<\/td>\nMin. 99.0%<\/td>\n<\/tr>\n
Solubility<\/td>\n<\/td>\nPractically insoluble in water, soluble in acetone, slightly soluble in ethanol (96%). It dissolves in strong acids; on dilution of the acid solutions with water, the base may be precipitated.<\/td>\n<\/td>\nAssay<\/td>\n<\/td>\n99.0% to 101.0% (anhydrous basis)<\/td>\n<\/tr>\n
Melting point<\/td>\n<\/td>\n174 – 177 \u00b0C<\/td>\n<\/td>\nStorage<\/td>\n<\/td>\nPreserve in well-closed container<\/td>\n<\/tr>\n
Water<\/td>\n<\/td>\nMax. 1.0%<\/td>\n<\/td>\nStability<\/td>\n<\/td>\nStable at least 2 years at R.T<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u0646\u0648\u0633\u06a9\u0627\u067e\u06cc\u0646 \u0628\u06cc\u0633 (Noscapine) \u0627\u0632 \u0622\u0644\u06a9\u0627\u0644\u0648\u0626\u06cc\u062f\u0647\u0627\u06cc \u0637\u0628\u06cc\u0639\u06cc \u06af\u06cc\u0627\u0647 \u062e\u0634\u062e\u0627\u0634 \u0648 \u0645\u062a\u0639\u0644\u0642 \u0628\u0647 \u062f\u0633\u062a\u0647 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0636\u062f \u0633\u0631\u0641\u0647 (Antitussive) \u0627\u0633\u062a \u06a9\u0647 \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u0645\u0627\u062f\u0647 \u0645\u0624\u062b\u0631\u0647 \u062f\u0627\u0631\u0648\u06cc\u06cc (API) \u062f\u0631 \u0634\u0631\u06a9\u062a \u062f\u0627\u0631\u0648\u0633\u0627\u0632\u06cc \u067e\u0631\u0646\u062f \u062f\u0627\u0631\u0648 \u062a\u062d\u062a \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u0647\u0627\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc \u0641\u0627\u0631\u0645\u0627\u06a9\u0648\u067e\u0647\u200c\u0627\u06cc (USP\u060c BP \u0648 JP) \u062a\u0648\u0644\u06cc\u062f \u0645\u06cc\u200c\u0634\u0648\u062f. \u0627\u06cc\u0646 \u062a\u0631\u06a9\u06cc\u0628 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0628\u0647 \u062f\u0644\u06cc\u0644 \u0633\u0627\u062e\u062a\u0627\u0631 \u0634\u06cc\u0645\u06cc\u0627\u06cc\u06cc \u0641\u062a\u0627\u0644\u06cc\u062f \u0627\u06cc\u0632\u0648\u06a9\u06cc\u0646\u0648\u0644\u06cc\u0646 (Phthalideisoquinoline)\u060c \u0641\u0627\u0642\u062f \u0627\u062b\u0631\u0627\u062a \u0645\u062e\u062f\u0631\u06cc\u060c \u0636\u062f \u062f\u0631\u062f\u06cc \u0648 […]<\/p>\n","protected":false},"author":1,"featured_media":379,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","footnotes":""},"categories":[36],"tags":[57],"class_list":["post-378","post","type-post","status-publish","format-standard","has-post-thumbnail","category-36","tag---noscapine"],"_links":{"self":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts\/378","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=378"}],"version-history":[{"count":1,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts\/378\/revisions"}],"predecessor-version":[{"id":380,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/posts\/378\/revisions\/380"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=\/wp\/v2\/media\/379"}],"wp:attachment":[{"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=378"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=378"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paranddarou.co\/Fa\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=378"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}